Install fails on mac os 10.12.5

I tried to follow the install instructions for blockstack core:


$ brew install gmp libffi openssl
$ sudo pip install --upgrade pip
$ sudo pip install blockstack --upgrade

But get the following errors:
Collecting jsonpointer>=1.9 (from jsonpatch<2,>=0.10->warlock>=1.3.0->blockstack-profiles>=0.14.1->blockstack)
Downloading jsonpointer-1.10-py2-none-any.whl
Installing collected packages: six, cachetools, base58, bitmerchant, keylib, keychain, bitcoin, pybitcoin, protocoin, simplejson, virtualchain, pyparsing, packaging, ipaddress, asn1crypto, enum34, pycparser, cffi, appdirs, setuptools, cryptography, jsontokens, blockstack-zones, functools32, jsonschema, jsonpointer, jsonpatch, warlock, blockstack-profiles, defusedxml, mixpanel, pycrypto, fastecdsa, basicrpc, boto, dropbox, blockstack
Found existing installation: six 1.4.1
DEPRECATION: Uninstalling a distutils installed project (six) has been deprecated and will be removed in a future version. This is due to the fact that uninstalling a distutils project will only partially uninstall the project.
Uninstalling six-1.4.1:
Exception:
Traceback (most recent call last):
File “/Library/Python/2.7/site-packages/pip-9.0.1-py2.7.egg/pip/basecommand.py”, line 215, in main
status = self.run(options, args)
File “/Library/Python/2.7/site-packages/pip-9.0.1-py2.7.egg/pip/commands/install.py”, line 342, in run
prefix=options.prefix_path,
File “/Library/Python/2.7/site-packages/pip-9.0.1-py2.7.egg/pip/req/req_set.py”, line 778, in install
requirement.uninstall(auto_confirm=True)
File “/Library/Python/2.7/site-packages/pip-9.0.1-py2.7.egg/pip/req/req_install.py”, line 754, in uninstall
paths_to_remove.remove(auto_confirm)
File “/Library/Python/2.7/site-packages/pip-9.0.1-py2.7.egg/pip/req/req_uninstall.py”, line 115, in remove
renames(path, new_path)
File “/Library/Python/2.7/site-packages/pip-9.0.1-py2.7.egg/pip/utils/init.py”, line 267, in renames
shutil.move(old, new)
File “/System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/shutil.py”, line 302, in move
copy2(src, real_dst)
File “/System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/shutil.py”, line 131, in copy2
copystat(src, dst)
File “/System/Library/Frameworks/Python.framework/Versions/2.7/lib/python2.7/shutil.py”, line 103, in copystat
os.chflags(dst, st.st_flags)
OSError: [Errno 1] Operation not permitted: ‘/tmp/pip-n8aqWk-uninstall/System/Library/Frameworks/Python.framework/Versions/2.7/Extras/lib/python/six-1.4.1-py2.7.egg-info’

What am i missing?
thanks